when I try to use this piece of code, it only works for 1 object, not for every. I'm trying to modify code from this video (https://www.youtube.com/watch?v=Idu8XfwKUao). Is there is a simpler way to get a result ?.If there is,please let me know

#part of code that doesn't matter
randomx = [100,400,300]
randomy = [100,0,300]
green_blob = pygame.image.load("greenblob-59x51.png").convert_alpha()
orange_blob = pygame.image.load("orangeblob-59x51.png").convert_alpha()
blob_mask = pygame.mask.from_surface(green_blob)
blob_color = green_blob
obstacle = []
obstacle_mask = []
oy = []
ox = []
for i in range(4):obstacle.append(pygame.image.load("obstacle-400x399.png").convert_alpha())obstacle_mask.append(pygame.mask.from_surface(obstacle[i]))ox.append(random.choice(randomx))oy.append(random.choice(randomy))
# main loop
while True:events()for i in range(4):mx, my = pygame.mouse.get_pos()offset = ((mx - int(ox[i]))), ((my - int(oy[i])))result = obstacle_mask[i].overlap(blob_mask, offset)if result:blob_color = orange_blobelse:blob_color = green_blobscreen.blit(obstacle[i], (ox[i], oy[i]))screen.blit(blob_color, (mx, my))pygame.display.update()CLOCK.tick(FPS)screen.fill(BLACK)

Your application works fine. The issue is, that result of each evaluation of overlap cause a change of blob_color. So the last obstacle in the loop "wins". If the last obstacle overlaps the blob, then the color is orange_blob, else it is green_blob.
Set the green color before the loop. If any obstacle overlaps the blob, then change it to orange. The blob has to be drawn once after the loop. e.g.:

while True:events()blob_color = green_blobfor i in range(4):mx, my = pygame.mouse.get_pos()offset = (int(mx - ox[i]), int(my - oy[i]))if obstacle_mask[i].overlap(blob_mask, offset):blob_color = orange_blobscreen.blit(obstacle[i], (ox[i], oy[i]))screen.blit(blob_color, (mx, my))

To find obstacle at random positions, which are not overlapping, you have to evaluate if a new obstacle hits any of the former obstacles.
Create a random position:

x, y = random.randint(100, 400), random.randint(100, 400)

And evaluate if there is any obstacle that overlaps the new position.

isect = any(obstacle_mask[j].overlap(obstacle_mask[i], (x-ox[j], y-oy[j])) for j in range(i))

If that is the case, then repeat the process. Create a new random position and test for overlapping:

obstacle = []
obstacle_mask = []
oy = []
ox = []
for i in range(4):obstacle.append(pygame.image.load("obstacle-400x399.png").convert_alpha())obstacle_mask.append(pygame.mask.from_surface(obstacle[i]))isect = Truewhile isect:x, y = random.randint(100, 400), random.randint(100, 400)isect = any(obstacle_mask[j].overlap(obstacle_mask[i], (x-ox[j], y-oy[j])) for j in range(i))ox.append(x)oy.append(y)